clonoSEQ is now covered by Medicare for MCL patients.
It is the first Medicare-reimbursed MRD test for patients with MCL and is clinically available as a CLIA-validated LDT.
For more information about incorporating clonoSEQ into your clinical practice for MCL patients, click here.
Ordering clonoSEQ
We’re here to guide you through the ordering process
The clonoSEQ testing service offers helpful support to make your experience seamless.
Actionable results
Delivered within approximately 7 days (fresh specimens) or 14 days (stored specimens) from the date of sample receipt and reconciliation.*
Online ordering completion
Patient data is securely stored in our Diagnostic Portal, eliminating the need for repetitive manual data entry.
Automated verification
Ensures each order includes all required information, reducing the likelihood of follow-up calls or processing delays.
Shipping materials provided
Upon request, we can provide kits to help collect and ship fresh, stored, and frozen specimens.
Secure report access
View and search results for your patients via our Diagnostic Portal, or opt-in to receive email or fax notifications when a new report is available.
Stored specimen retrieval support
Given permission, we can contact outside pathology labs to obtain access to stored diagnostic specimens for Clonality (ID) testing.
How to place your first order:
Contact us using the form below if you need access to our Diagnostic Portal. If you already have an account, log in here.
A representative will reach out to finish setting up your account.
Once you have access to the Diagnostic Portal, create a clonoSEQ Test Requisition Form (TRF) by placing a new order.
Ship your samples with a copy of the clonoSEQ Test Requisition Form (TRF) to Adaptive. Your results will be available to view in the Diagnostic Portal.
Need help navigating the Diagnostic Portal?
Check out our clonoSEQ Portal Walkthrough
clonoSEQ is available to healthcare providers via Epic integration.
We continue to expand access to clonoSEQ by offering it as a fully integrated test in Epic Aura. If you currently place lab orders in your Epic system, this integration is available for no additional cost. If you wish to learn more, contact your Adaptive account representative or Adaptive’s Integration Specialists at emrsupport@adaptivebiotech.com.
Adaptive Clinical Services Team
Call 1-888-552-8988, opt. 1 from 5:30 am to 5 pm PT, Monday through Friday, or email clinicalservices@adaptivebiotech.
Laboratory Shipping Address
Adaptive Biotechnologies
Attention: CLIA Clinical Laboratory
1165 Eastlake Avenue E
Seattle, WA 98109
Intake Hours
Monday–Saturday
8 am to 5 pm PT
Laboratory Licenses
View our CAP accreditation and our CLIA license.
Biological specimens can be received and accessioned on the days and times above.
Samples cannot currently be received on Sundays.
Looking for more information or downloadable resources?
Frequently asked questions
I am interested in ordering clonoSEQ. How do I get started?
To get started, contact us using the form above to gain access to our Diagnostic Portal. A representative will reach out to finish setting up your account. Once you have access to the Diagnostic Portal, you can login to place clonoSEQ orders and view patient results. We’ll help guide you through the ordering and send out process, and can provide resources to ensure success with specimen selection, ordering, and send out.
How do I place a clonoSEQ order?
All Test Requisition Forms (TRFs) must be completed through our easy-to-use, secure online Diagnostic Portal. Please contact Clinical Services at 888-552-8988 for information on how to set up an account.
What are the requirements for shipping?
Once you have completed a TRF within the Diagnostic Portal, please print, sign and date the TRF.
- If you are shipping a specimen for testing, you must include the signed TRF inside the box containing the specimen.
- If you are requesting pathology retrieval assistance from Adaptive, please send the TRF by secure email or fax to Clinical Services.
If you indicate on the TRF that your test order should be billed to the patient’s insurance, a front/back copy of the patient’s insurance card must be included with the TRF.
If you are shipping a specimen, please be sure to:
- Follow the preparation and shipping instructions specified in the clonoSEQ Test Specimen Requirements, which are accessible on the Downloadable Resources page.
- Label the specimen tube with 2 unique patient identifiers to ensure proper identification.
Adaptive can provide a clonoSEQ Fresh Collection Kit and a clonoSEQ Frozen Shipper. To order, please contact Clinical Services. You may also use your own packaging materials; ship to the address listed at the top of this page.
How do I request pathology retrieval assistance?
If desired, Adaptive can assist with the retrieval of archived pathology specimens. Requests for this assistance must be indicated in the Specimen Information section of the TRF. To enable pathology specimen retrieval, the patient’s complete pathology report must be included with the signed TRF.
Adaptive aims to provide accurate and timely patient results. You can expect to receive results in approximately 7 days for fresh specimens and 14 days for stored specimens, measured from the date that an appropriate sample is received and reconciled in Adaptive’s Seattle laboratory. Samples that arrive without requisite information will require additional time to reconcile.
Adaptive must have a valid Clonality (ID) Test result in order to generate a Tracking (MRD) Test result for a given patient. Delivery of clinical reports containing MRD results will be delayed until a corresponding Clonality (ID) result becomes available.
If you are requesting Adaptive assistance with pathology specimen retrieval, please note that lab response times to our requests vary considerably. The turnaround times listed above are measured from the date Adaptive receives and reconciles an appropriate specimen. Turnaround times do not include time required for specimen retrieval. If specimen retrieval is urgent, Adaptive recommends that the clinician request and submit the specimen directly from the pathology lab.
How long will it take to get patient results back?
Adaptive aims to provide accurate and timely patient results. You can expect to receive results in approximately 7 days for fresh specimens and 14 days for stored specimens, measured from the date that an appropriate sample is received and reconciled in Adaptive’s Seattle laboratory. Samples that arrive without requisite information will require additional time to reconcile.
Adaptive must have a valid Clonality (ID) Test result in order to generate a Tracking (MRD) Test result for a given patient. Delivery of clinical reports containing MRD results will be delayed until a corresponding Clonality (ID) result becomes available.
If you are requesting Adaptive assistance with pathology specimen retrieval, please note that lab response times to our requests vary considerably. The turnaround times listed above are measured from the date Adaptive receives and reconciles an appropriate specimen.
Turnaround times do not include time required for specimen retrieval. If specimen retrieval is urgent, Adaptive recommends that the clinician request and submit the specimen directly from the pathology lab.
How will I receive the patient report?
You can easily access patient results through Adaptive’s Diagnostic Portal—the same portal that you will use to complete clonoSEQ TRFs.
- The Diagnostic Portal enables you to filter and sort patient reports so that you can find specific reports quickly and easily.
- Upon release of new patient results, you will receive an email notification with a direct link to your patient’s report. You can also choose to have patient results delivered via secure fax.
- You will only receive one email or fax notification per order, at the time when all results for the patient’s order are available. Results of individual tests within an order will always be available in real-time in the Diagnostic Portal.
*Reconciliation ensures all required information and documentation is correct for the patient, clinician, institution, order, and sample. In cases where a sample must be retrieved from a pathology lab and/or has been stored under certain conditions, reconciliation will add additional time to the testing process.
This page is intended for a US-based audience.
clonoSEQ® is available as an FDA-cleared in vitro diagnostic (IVD) test service provided by Adaptive Biotechnologies to detect measurable residual disease (MRD) in bone marrow from patients with multiple myeloma or B-cell acute lymphoblastic leukemia (B-ALL) and blood or bone marrow from patients with chronic lymphocytic leukemia (CLL). Additionally, clonoSEQ is available for use in other lymphoid cancers and specimen types as a CLIA-validated laboratory developed test (LDT). To review the FDA-cleared uses of clonoSEQ, visit clonoSEQ.com/technical-summary.